What We Do Apply For Research Funding Apply for Research Funding Our Mission The Duchenne UK mission is to End Duchenne in Ten. The research projects that we currently fund have been selected with this mission uppermost in our minds. Likewise, as we evaluate projects for future funding, the first question we will ask is ‘does this research have the potential to help end Duchenne in Ten?’ Extensive research into both the molecular basis and the pathophysiology of Duchenne over the last 30 years has led to the development of a number of strategies for treatment. Gene and cell-based therapies that aim to deliver the missing DMD gene and/or the protein dystrophin hold great promise for the future. In addition to those potentially disease-modifying strategies, an exciting array of pharmacological approaches that target the downstream pathology, resulting from insufficient dystrophin in muscles, are being investigated. Duchenne UK is leading the way to the brighter future for families and people living with Duchenne. We are doing this by: Spending 90% of monies raised directly on research Commissioning world-class research projects Supporting promising research wherever in the world it is happening Collaborating with academics and Universities Working with Biotech and Pharmaceutical companies, big and small Increasing the capacity for research at hospitals in the UK so more people with Duchenne can participate in clinical trials Engaging with regulators to find ways of speeding up access to promising new treatments Sharing ideas and knowledge with families and people living with Duchenne. We are interested in funding research which has the potential to be a step on the way to our mission to End Duchenne in Ten. Make A Proposal We will consider all proposals whether from Industry, academia or clinicians. The research proposal should clearly document the following for the project: background hypothesis that will be tested experimental or project plan output expected resources available simple Gantt showing timeline and milestones detailed costing how the proposed project translates to our mission to End Duchenne in Ten other funding sought references Proposals that we feel have the potential to be a step on the way to ‘End Duchenne in Ten’ will be reviewed by our Scientific Advisory Board members and also by our Patient Advisory Board. Indirect Costs Much of the funding from Duchenne UK goes to support research in Universities where research proposals are costed for direct and indirect costs. Direct costs are all those directly chargeable to a project and include staff time, consumables and equipment. Indirect costs are non-specific costs such as administration, IT and buildings, which are charged across all projects for underpinning resources. As we are a charity and our donors expect that the money they give will be spent on researching new treatments, Duchenne UK does not pay the indirect research costs of any University based project. Contact Us If you would like to discuss an idea for a research project or make a proposal for us to consider funding, please contact us in the first instance by sending an e-mail to our Director of Research, David Bull: [email protected].