About DMD

Duchenne muscular dystrophy (DMD) is a progressive condition diagnosed in childhood. It causes all the muscles in the body to gradually weaken.

There is currently no cure for Duchenne, but there is hope. We are at the forefront of advancing treatments and care for everyone affected by the disease.

A boy with DMD taking part in a Duchenne UK gaming day

What is Duchenne muscular dystrophy?

DMD is a genetic disease that causes muscle weakness and wasting. It is the most common and severe form of muscular dystrophy.

It is caused by a fault, known as a mutation, on the dystrophin gene. Dystrophin is a protein that protects muscles; without it, muscles are easily damaged, and their strength and function is weakened. It eventually affects all the muscles in the body, including the heart and lungs.

DMD almost always affects boys. It is typically diagnosed in childhood between the age of three and six.

Learn more about DMD causes and stages

DMD in numbers

DMD is classified as a rare disease, but it is one of the most frequent genetic conditions. It mainly affects males, and can affect any ethnicity. The following statistics are approximations.

Doctor with young boy

Clinical trials for DMD

Clinical trials are research studies that explore whether a medical treatment is effective and safe for humans.

Duchenne UK launched the DMD Hub in 2016 to address the lack of clinical trials for DMD available in the UK. The DMD Hub is a network of trial sites with trained staff, funded to carry out clinical trials for DMD.

About DMD clinical trials

Treatments for DMD

Current treatments

Find out about current approved treatments and supporting therapies for DMD.

Current treatments Current treatments

Treatments in the pipeline

Duchenne UK are funding research to bring more effective treatments to patients, faster.

Research we fund Research we fund
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Join a community of families affected by DMD and get the support and guidance you need.

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